Key in this game is not turning the ball over also stick with the run game, IMO, Henderson could have a big game because of his explosiveness, hopefully, he doesn't get dinged up. Move Goff around and lean on the TE's, which hopefully open up Kupp & Woods.
I believe in the defense and hopefully with no turnovers or any special teams snafu's they won't be put in a bad position. Gay needs to ensure all his kicks are out of the end zone and Webster needs to secure the ball to ensure he does not put the ball on the ground. If the Rams can win the turnover battle or break even, IMO, they win the game.