Rams vs. 49ers odds, line: Proven model reveals NFL picks, predictions for Thursday Night Football matchup - SportsLine.com
The SportsLine Projection Model has simulated Los Angeles Rams vs. San Francisco 49ers 10,000 times and revealed its Week 15 NFL picks
Pick: 49ers -129
San Francisco is winning outright in 71% of simulations.
Projected final score: 49ers 30, Rams 20