Rams are lookin at either the 3 or 4 seed. Since it doesn't have the option of adding a bye (i.e. we have no chance of getting the 1 or 2 seeds) I would rest the starters. No doubt about it. Health is #1 priority going into the playoffs IMO.
IF the Saints jump us then most likely the impact is we face the Panthers instead of Falcons/Seahawks. Whoopideedoo.
Round 2 impact is that we'd probably draw the Eagles. I don't expect either the Rams or Saints to lose in round 1, so the Eagles matchup is preferred over going to Minnesota.
NFC Championship round impact is that we might end up going to New Orleans instead of Minnesota. If that does happen, it's a godsend IMO, as the Vikings are our worst matchup.
Rest the starters. Just do it.