I'm sure the conventional answer is to say OT but if you look at all the teams that have taken an OT at the top and those players turned out to be Pro-Bowlers, I don't think many have even gone to the playoffs(if they did, they didn't go far). For example, Joe Thomas, Jake Long, Matt Kahlil, etc have all been drafted very high yet their respective teams have done nothing. Players like Okung and Clady were also drafted high but if you look a little deeper, you'll see that they've been injured and their teams haven't really missed them at all. Many of the top teams do just fine with average to solid LT play. (Here's an article I accidentally stumbled upon when looking for all the recent OT's that were taken high that agrees with me:
http://mmqb.si.com/2013/10/30/nfl-offensive-tackles-rethinking-the-blind-side-and-position-value/).
Now look at all the top teams in the NFL and you'll almost always find an stud WR or TE for the QB to throw to. Baltimore, NY Giants, N.O., Green Bay, etc all had elite, or at least very good, WR's or TE's when they won.
So to answer the original question, I'd rather take the DE or WR over a LT. There's very little evidence that in today's game an elite LT is needed.