OK people, don't go to the East side unless you are with a guide you know and trust. Seriously. I don't care if you are a badass or what color, sex, religion, nationality, or sexual preference is. Be wise. Some of those clubs are no go zones.
As far as places with hot chicks, go to the west end. That's a place, not so much a direction. It's a place for great food, music, and eye candy, but also the place you are likely to meet, um, metrosexuals? Is that still allowed? It's fun, and popular. Some expense involved, but Missouri expense, not LA expense.
The Arch grounds are destroyed with a massive renovation. It's sad because it could have had a great event at this time. You can go into it and up to the lookout, but that's it. Better to get the tickets online or go to the old courthouse.
By the way, the old courthouse is worthy of a looksee. Very cool.
I'm suggesting the Tigin to meet up just because it's close and has a nice beer selection. We either walk East to the landing, which has some good points, or 3/4 of a mile to ballpark village, which will probably be hopping also. The difference is old school (landing) vs franchise (ballpark). However, there are a dozen other choices too.
The west end requires a short ride of some sort.
I think the best idea would be to group up early at Tigins in the Hampton Inn, meet and greet, close to everyone, and separate based on what people like. Local flavor and beer, go east to the landing. Bright and new, go south to ballpark. Still, there is great food and music to be had all over, so that's not a limitation.
I'm totally down with a blues band myself, I provided options if anyone is interested.