It is interesting to look back at the 2010 draft. At no. 1, the Rams went with the top prospect at the game's most valuable position. It's hard to argue. There was bad luck combined with an inability to build around him.
One could also argue there were many talented players in the first round that year, some borderline HOFers, and that the Rams needed help at virtually every position. The four players who went directly after Bradford all went to at least five Pro Bowls.
Rams did OK going Bradford, then Saffold with their first two picks. But after that...yeesh. Jerome Murphy, Marty Gilyard, "Illinois Mike", then Fendi Onobun. Everson Griffen went one pick after Gilyard, and Kam Chancellor one pick after Hoomananawui. I remember, I hated the way the Rams addressed TE in that draft. It might've been the weakest position on the offense. They passed on five or six more talented prospects before the two they did take, produced nothing.
Meanwhile the Seahawks came away with Earl Thomas, Chancellor, Russell Okung, and Golden Taint, setting them up for the next few years.
Pro Football Reference still regards Suh as being the most valuable player in the 2010 draft. He is never hurt and usually reasonably productive as a player. Still, I wonder how his career will be looked at when he comes up for HOF eligibility. He came into the league with a massive amount of hype, was hugely productive in college. Came in like he was going to dominate the league his first year. At least with the Lions, he was one of the league's top defensive lineman. Ever since he went to Miami, it feels like he's been a good but not great player. 70 career sacks, five Pro Bowls....that may not be enough to get him into the Hall.
AD99 was the best player in his draft and undoubtedly would've gone no 1 overall if teams knew what he was going to become. He has changed the way people look at DTs. I would still be leery about drafting one ahead of a top QB. There were a lot of high profile busts at D tackle before Suh came into the league. I remember one scout saying, that defensive tackle was difficult to evaluate at the college level, and that teams do more projecting than they would at other positions.
AD is what he is, a generational talent, but even with top defensive tackle prospects in future drafts, I think you have to accept none of them are going to be Aaron Donald, but something less.